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The QCRG (Quantitative Biosciences Institute Coronavirus Research Group), one of the NIH Antiviral Drug Discovery (AViDD) Centers for Pathogens of Pandemic Concern is funding four Developmental Research Projects. The goal for these collaborative grants is to advance QCRG’s mission to develop clinical drug candidates with potent in vivo antiviral activity against viruses of pandemic concern, and advance a readily shared platform of technologies and target strategies applicable also to future pandemics.
QCRG AViDD is also funding two Mentored Project Awards for early-career researchers. The goal for these mentored projects is to advance QCRG’s mission to develop clinical drug candidates with potent in vivo antiviral activity against viruses of pandemic concern, and advance a readily shared platform of technologies and target strategies applicable also to future pandemics.
Learn more about the awardees and their projects!
Project: "Targeting SARS-CoV-2 Orf9b for Antiviral Therapies"
Project: "Leveraging High-Throughput Microfluidic Technologies to Quantify Drug Resistance"
Project: "Development of Novel Antiviral Agents Targeting Viral Helicases"
Project: "Development of papain-like protease inhibitors as SARS-CoV-2 antivirals"
Project: "Developing screening methods to discover the next generation of SARS-CoV-2 MPro inhibitors"
Project: "Leveraging differences in conformational entropy of macrodomain genetic variation to gain molecule binding affinity and specificity"
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